Purine nucleosides
Medchemexpress LLC 2'-Deoxyadenosine monohydrate | 16373-93-6 | 99.9% | 269.26 | 50 G
2'-Deoxyadenosine monohydrate is an adenine nucleoside that inhibits glucose-stimulated insulin release. It also inhibits glucose-stimulated increases in islet cyclic AMP (cAMP) accumulation, activates caspase-3, promotes apoptosis, and inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH). Additionally, it inhibits the growth of various cells and exhibits an anticancer effect on colon cancer.
- Inhibits glucose-stimulated insulin release.
- Inhibits glucose-stimulated increases in islet cyclic AMP (cAMP) accumulation.
- Activates caspase-3 and promotes apoptosis.
- Inhibits the activity of S-adenosyl-L-homocysteine hydrolase (SAHH).
- Inhibits the growth of various cells.
- Has an anticancer effect on colon cancer.
Medchemexpress LLC N6-cyclopentyladenosine | 41552-82-3 | MFCD00036845 | 100.0% | 335.36 g/mol | C15H21N5O4 | 1 ML
N6-Cyclopentyladenosine is a selective adenosine A1 receptor agonist used as a research reagent in pharmacology and receptor signaling studies. Supplied as a 10 mM solution in a 1 mL vial, it is intended for in vitro experiments and receptor-binding assays.
- Selective adenosine A1 receptor agonist for pharmacological studies.
- Provided as a 10 mM solution for ready-to-use experiments.
- High chemical purity suitable for research applications.
- Compact 1 mL vial format for small-scale assays.
- Molecular weight 335.36 g/mol; molecular formula C15H21N5O4.
Chem-Impex International, Inc. 2'-Deoxyadenosine monohydrate | 16373-93-6 | MFCD00149364 | 1G
2'-Deoxyadenosine monohydrate, 16373-93-6, MFCD00149364, 1G
Medchemexpress LLC 8-Bromo-2'-deoxyadenosine | 14985-44-5 | ≥98.0% | 330.14 | 50 MG
8-Bromo-2'-deoxyadenosine is a purine nucleoside analog. These analogs possess broad antitumor activity, specifically targeting indolent lymphoid malignancies. Their anticancer mechanisms involve inhibiting DNA synthesis and inducing apoptosis.
- Purine nucleoside analog
- Has broad antitumor activity
- Targets indolent lymphoid malignancies
- Inhibits DNA synthesis
- Induces apoptosis
Medchemexpress LLC 6-Thio-2'-deoxyguanosine | 789-61-7 | 99.7% | 283.31 | 10 MG
6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase. This compound has shown rapid cell death in various cancer cell lines with IC50 values between 0.7-2.9 μM. In A549 lung cancer cell-based mouse xenograft studies, it decreased tumor growth rate, outperforming 6-thioguanine treatment, and increased telomere dysfunction in tumor cells in vivo. It is for research use only.
- Nucleoside analogue
- Incorporated into de novo-synthesized telomeres by telomerase
- Induces rapid cell death in various cancer cell lines
- Decreases tumor growth rate in mouse xenograft studies
- Increases telomere dysfunction in tumor cells in vivo
Apexbio Technology LLC 6-O-Propynyl-2-deoxyguanosine 25mg
6-O-Propynyl-2-deoxyguanosine (CAS 1640051-47-3) is a modified nucleoside featuring an alkyne functional group at the 6-position of deoxyguanosine This structural modification enables its use in bioorthogonal click chemistry reactions facilitating site-specific labeling and conjugation in nucleic acid research The alkynyl group serves as a chemical handle for copper-catalyzed azide-alkyne cycloaddition allowing researchers to attach probes or other functional molecules 6-O-Propynyl-2-deoxyguanosine is utilized for studying DNA structure dynamics and for the development of modified oligonucleotides in biochemical and molecular biology assays
Medchemexpress LLC Adenosine, 8-bromo-2'-deoxy- | 14985-44-5 | ≥98.0% | 330.14 | 10 MM 1 ML
8-Bromo-2'-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
- Exhibits broad antitumor activity
- Targets indolent lymphoid malignancies
- Inhibits DNA synthesis
- Induces apoptosis
Medchemexpress LLC Peonidin-3-O-arabinoside chloride | 524943-91-7 | 98.5% | 468.84 | 25 MG
Peonidin-3-O-arabinoside chloride is an anthocyanin that can be isolated from *Vaccinium myrtillus L.*. This chemical compound is available as a solid with high purity, suitable for various research applications.
- High purity: 98.5%
- Solid appearance
- Brown to black color
- Recommended storage at 4°C, sealed, away from moisture
- Extended storage in solvent at -80°C (6 months) or -20°C (1 month)
Apexbio Technology LLC 6-O-Propynyl-2-deoxyguanosine 1mg
6-O-Propynyl-2-deoxyguanosine (CAS 1640051-47-3) is a modified nucleoside featuring an alkyne functional group at the 6-position of deoxyguanosine This structural modification enables its use in bioorthogonal click chemistry reactions facilitating site-specific labeling and conjugation in nucleic acid research The alkynyl group serves as a chemical handle for copper-catalyzed azide-alkyne cycloaddition allowing researchers to attach probes or other functional molecules 6-O-Propynyl-2-deoxyguanosine is utilized for studying DNA structure dynamics and for the development of modified oligonucleotides in biochemical and molecular biology assays
Medchemexpress LLC Malvidin-3-O-arabinoside chloride | 28500-04-1 | 97.1% | 498.86 | 5 MG
Malvidin-3-O-arabinoside chloride (M3A chloride) is a research chemical that ameliorates ethyl carbamate-induced oxidative damage by stimulating AMPK-mediated autophagy. It is used in studies to understand cellular processes related to oxidative stress and autophagy.
- Stimulates phosphorylation of AMP-activated protein kinase (AMPK)
- Upregulates LAMP-1 expression
- Restores lysosomal acidity and strengthens lysosomal functions
- Inhibits excess reactive oxygen species (ROS) generation
- Enhances glutathione (GSH) levels and autophagy flux
- Upregulates LC3-II/LC3-I ratio
Medchemexpress LLC 2'-Deoxyadenosine monohydrate-13C10,15N5 hydrate | 2483830-27-7 | 99.7% | 284.15 | 1 MG
2'-Deoxyadenosine monohydrate-13C10,15N5 hydrate | 2483830-27-7 | 99.7% | 284.15 | 1 MG
Cambridge Isotope Laboratories 2-Fluoro-2-deoxyguanosine 5-triphosphate ammonium salt (unlabeled) (in solution) CP 90% 100 umol
2-Fluoro-2-deoxyguanosine 5-triphosphate ammonium salt (unlabeled) (in solution) CP 90% 100 umol
